Joint GSU/GaTech Invitee
Neuroscience, Neuroimaging, Neuroethics 2CI Groups
Dr. Read Montague
“Social Exchange and the Effort to Phenotype Cognition”
Computational ideas now play a central role in our understanding of cognition and its origins in the function of neural tissue. Nevertheless, computational depictions of cognitive function have had little impact on the way we assess mental function in healthy brains or in the presence of disease or injury. In this talk I will present our efforts to use simple social exchange tasks to decompose interactions with other humans into component parts with the goal of identifying the way these parts function in health and display dysfunction in disease or injury.
Monday January 13, 2014
10:30 a.m. to noon
124 Parker H. Petit Science Center at GSU
“Sub-second dopamine recordings in humans during sequential decision-making tasks”
One goal of neuroscience is to understand the connection between physical events in the brain and the mental states and behavioral output that such events support. One of the physical events thought to be important is the dynamic release and action of neurotransmitter molecules; however, there are no examples where moment-by-moment (sub-second) fluctuations in neurotransmitter levels have been related to quantitatively characterized behavior in humans. We have developed the capacity to make sub-second measurements of the neurotransmitter dopamine in human subjects during active decision-making experiments and connected the measured dopamine dynamics to variables important for making choices in simple, sequential decision-making tasks. These measurements have been made using an electrochemical technique called fast scan cyclic voltammetry in subjects being implanted (for clinical reasons) with deep brain stimulating electrodes. This work is in its early stages but may open the way for the development of other invasive and non-invasive methods for neurotransmitter tracking in humans.
Tuesday January 14, 2014
Parker H. Petit Institute for Bioengineering and Bioscience
Suddath seminar room at GaTech