Category: Talks

Upcoming and previous talks

November 16th, 2010

What: Brain Imaging Series Lecture
When: TUESDAY, November 16, 2010 3:15-4:15pm
Who: Free, Open to the public
Where: Center for Advanced Brain Imaging, Conference Room

“Biomagnetics: An interdisciplinary field where magnetics, biology and medicine overlap.”

Prof. Shoogo Ueno
Kyushu University/Teikyo University/The University of Tokyo

Biomagnetics is an interdisciplinary field where magnetics, biology and medicine overlap. It has a long history since 1600, when William Gilbert published his book De Magnete. Recent advances in biomagnetics have enabled us not only to detect extremely weak magnetic fields from the human brain, but also to control cell orientation and cell growth by extremely high magnetic fields. Pulsed magnetic fields are used for transcranial magnetic stimulation (TMS) of the human brain, and both high frequency magnetic fields and magnetic nanoparticles have promising therapeutic applications for treatments of cancers and brain diseases such as Alzheimer’s and Parkinson’s. On the imaging front, magnetic resonance imaging (MRI) is now a powerful tool for basic and clinical medicine. New methods of MRI based on the imaging of impedance of the human body, called impedance MRI, and the imaging of neuronal current activities in the human brain, called current MRI, are also being developed.

This lecture focuses on the advances in biomagnetics and bioimaging obtained mostly in our laboratory in recent years. The lecture describes: (1) a method of localized magnetic stimulation of the human brain by TMS with a figure-eight coil; (2) magneto-encephalography (MEG) to measure extremely weak magnetic fields produced from brain electrical activity using superconducting quantum interference device (SQUID) systems; (3) impedance MRI and current MRI; (4) cancer therapy and control of iron-ion release from, and uptake into, ferritin, an iron-storage protein, by using both high frequency and pulsed magnetic fields and magnetic nanoparticles; and (5) magnetic control of biological cell orientation and cell growth by strong static magnetic fields. These new biomagnetic approaches will open new horizons in brain research, brain treatment, and regenerative medicine.

Shoogo Ueno is the IEEE Magnetics Society Distinguished Lecturer. He received the B.S., M.S. and Ph.D. (Dr. Eng.) degrees in electronic engineering from Kyushu University, Fukuoka, Japan, in 1966, 1968, and 1972, respectively. He subsequently served as a professor in the Department of Electronics, Kyushu University (1986-1994) and in the Department of Biomedical Engineering, Graduate School of Medicine, University of Tokyo (1994-2006). Since 2006 he has been a professor with the Department of Applied Quantum Physics, Graduate School of Engineering, Kyushu University, and dean of the Faculty of Medical Technology, Teikyo University, Fukuoka.

Dr. Ueno is a Fellow of the IEEE (2001) and of the American Institute for Medical and Biological Engineering (2001). He is a Fellow and Member-at-Large of the Governing Council of the International Academy for Medical and Biological Engineering (2006). He was an elected member of the IEEE Magnetics Society Administrative Committee (2004-2009). He was President of the Bioelectromagnetics Society (2003-2004), Chairman of the International Union of Radio Science’s Commission K on Electromagnetics in Biology and Medicine (2000-2003), President of the Japan Biomagnetism and Bioelectromagnetics Society (1999-2001), President of the Magnetics Society of Japan (2001-2003), and President of the Japanese Society for Medical and Biological Engineering (2002-2004). He received the Doctor Honoris Causa from Linkoping University, Linkoping, Sweden (1998). He was a 150th Anniversary Jubilee Visiting Professor at Chalmers University of Technology, Gothenburg, Sweden (2006), and a visiting professor at Simon Frasier University, Burnaby, Canada (1994) and Swinburne University of Technology, Hawthorn, Australia (2008).

Posted in Talks

October 20, 2010

What: Brain Imaging Series Lecture
When: October 20, 2010 3:15-4:15pm
Who: Free, Open to the public
Where: Coon Building, room 250

Gregory Samanez-Larkin, PhD
Department of Psychological Sciences, Vanderbilt University

Title: Value-Based Learning and Decision Making in the Aging Brain

Abstract: As the proportion of older adults continues to grow rapidly here in the U.S. and across the globe, aging adults may be required to make more independent health-related and financial decisions. Thus, it is increasingly imperative to better understand the impact of age-related psychological changes on decision making. Although a growing body of research has linked age-related deficits in attention, memory, and cognitive control to changes in medial temporal and lateral prefrontal cortical function, remarkably little research has investigated the influence of aging on valuation and associated mesolimbic function in the striatum and medial prefrontal cortex. In this talk I will present a set of experiments focused on age differences in value-based learning and decision making. Overall, neuroimaging results suggest that age-related changes in mesolimbic function (e.g., changes in signal variability and the representation of prediction errors) are associated with changes in learning and decision making. Importantly, follow-up behavioral experiments also reveal that age-related impairments are reduced or eliminated under supportive task conditions. I will also briefly discuss some of the methodological issues with comparing younger and older adults using neuroimaging, and how these issues can be addressed.

Posted in Talks